To study the correlation between the pressure-to-cornea index and both structural and functional measures of glaucoma


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Article type :

Original Article

Author :

Shail Shah, Rajni Sethia, R N Kothari, Aakash Patel, Hushedar Kharas

Volume :

6

Issue :

2

Abstract :

Background: Pressure to cornea index was proposed in order to integrate intraocular pressure and central cornea thickness as a single risk factor for glaucoma. PCI could better reflect the individual susceptibility to glaucomatous damage than either IOP or CCT by itself. Aim of this study was to find correlation between the pressure-to-cornea index with structural and functional measures of glaucoma. Materials and Methods: In this cross sectional study, PCI was calculated for 100 eyes of 53 patients (ocular hypertension, primary open angle glaucoma, normal tension glaucoma and controls). Cup to disc ratio, mean deviation(MD) and pattern standard deviation (PSD) as recorded by Humphrey automated perimetry (SITA 24-2) were correlated with PCI. Results: The difference in the value of PCI among different groups was statistically significant (p=0.000). There was positive correlation between PCI and C/D (p=0.000); negative correlation between PCI and MD (p=0.000); and positive correlation between PCI and PSD(p=0.106). Conclusions: We conclude that PCI can be used as a unified risk factor. Also we have found statistical correlation between structural and functional measures of glaucoma to pressure to cornea index (PCI). Hence, we conclude that it can be used for evaluating glaucoma severity as well.

Keyword :

 Glaucoma, PCI, PSD, CCT.
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