Assessment of serum levels of ascorbic acid and malondialdehyde as oxidative stress marker in patients with oral lichen planus


Article PDF :

Veiw Full Text PDF

Article type :

Original Article

Author :

Geetha Khimavath, Anil Kumar A S, Sowmya Krishna, Ashwin Kumar

Volume :

7

Issue :

4

Abstract :

Background: Oral Lichen Planus (OLP) is a chronic inflammatory mucosal disease with unknown etiology. The cause might because of reactive oxygen species and oxidative damage to the tissues.In recent studies, free radicals have been postulated as the possible etiology of inflammatory and autoimmune disease. Materials and Methods: A total of 60 participants were studied and they were grouped in to cases and controls. Each group had 30 participants, 30 cases and 30 healthy controls. Serum levels of MDA and Vitamin C were estimated. The data collected was analyzed statistically by using descriptive statistics namely mean, standard deviation and any significant difference between the mean values of cases and controls will be tested by using sample Student t-test. A p value

Keyword :

 Serum Ascorbic Acid (vitamin C), Malondialdehyde (MDA) levels.
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