Abstract :
Wound healing is one of the most complex and dynamic processes in the body of the human. Wound healing is an essential biological development to sustain the integrity of skin after trauma, either by accident or by a deliberate process. In the phases of hemostasis, inflammation, development, re-epithelialization, and remodeling, this includes the spatial and temporal coordination of many cell types with different functions. In understanding the mechanisms of normal wound closure, it is important to unravel the
functions of these cell types and their interactions with each other. Micro-environmental changes, including changes in mechanical forces, levels of oxygen, chemokines, extracellular matrix, and synthesis of growth factor, directly influence cellular recruitment and activation, leading to disrupted wound healing conditions. Wounds are cured with different medicinal plants or from their extracts. Plants supply humans with different medicines, and medicinal plants are the blessing of nature used to heal wounds with even lower side effects. This systematic review aims to explain the physiology of the wound healing process, different cellular, and
molecular aspects, and to provide insight into the various plants that have possible wound healing properties that could be valuable in healing practice.
Keyword :
Wound healing, Skin injury, Hemostasis, Inflammation, Reepithelialization, Remodelling, medicinal plants.