Abstract :
Background: The prevalence of metabolic syndrome is increasing in Indian population, predisposing an increased risk for
the development of diabetes mellitus and cardiovascular diseases. Methods: A case control study was conducted to
assess the prevalence of MS and the association between the components of MS in 250 patients, diagnosed by
angiography to have CAD (125 patients) as cases and no CAD (125 patients) as control group. MS was diagnosed based
on the modified ATP III guidelines, if three or more of the following were present: abdominal obesity, hypertension, glucose
intolerance, hypertriglyceridemia or low HDL-C levels. SPSS Version 15 was used for statistical analysis and Chi-square
analysis was used to estimate the prevalence of MS with respect to the severity of CAD, family history of CAD and smoking
history. The association between individual risk factor and outcome was estimated using univariate logistic regression. The
multivariate logistic regression analysis was used to estimate the components of MS as a risk factor for CAD, controlling
the other confounders. A P value of
Keyword :
metabolic syndrome, CAD, diabetes.